Examining and identifying function and role of LPHN3 in ADHD Specific Aim 1: LPHN3 KO, heterozygous (HET), and WT littermates, will be comprehensively assessed for working memory-based attention, sensory-mediated attention, cognitive flexibility, impulsivity, and...
Exploring the role of the oncogene Dek as a novel player in Alzheimer’s disease. Neurocognitive disorders (including Alzheimer’s disease) currently affect 35 million people in the United States. These disorders exact a significant emotional, physiological,...
Developing a neuron replacement therapy to improve breathing, motor function and survival in neurodegenerative disease Developing a neuron replacement therapy to improve breathing, motor function and survival in neurodegenerative disease. Respiratory failure is the...
Proteomic and genomic investigation of PSD-95 protein-protein interactions in schizophrenia This is an innovative LIFE application to investigate abnormalities of brain health in schizophrenia, It is an understatement to say that the treatment of schizo-spectrum...
Non-invasive IPSC-based Therapies for Treatment of Neurodegenerative Diseases Awarded $100,000 Mental disorders including neurodegeneration are expected to affect increasing populations as life expectancy increases, representing an enormous economic and health burden....
